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RESTORE SKIN'S NATURAL DEFENCE

UNDERSTAND SKIN MICROBIOME

A CRUCIAL ROLE IN MAINTAING SKIN HEALTH

The skin microbiome refers to the diverse community of microorganisms, including bacteria, fungi, viruses, and mites, that reside on the skin's surface. These microorganisms coexist with our skin cells in a balanced ecosystem.

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The skin's microbiome acts as a protective barrier by occupying space on the skin's surface and competing with harmful pathogens for resources. This competition limits the growth of potentially harmful microorganisms, reducing the risk of skin infections and diseases.

Natural Beauty

THE SKIN
EXTRAORDINARY ECOSYSTEM

Regulates skin immunity

The skin microbiome plays a vital role in training and modulating the immune system. It helps to fine-tune immune responses, making the skin more efficient in recognising and combating pathogens while reducing the risk of inflammatory reactions and allergies.

Maintains skin barrier function

A healthy skin microbiome helps support the skin's natural barrier function. It aids in the production of essential lipids and proteins that form the skin's protective barrier, preventing excessive moisture loss and keeping the skin hydrated.

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INBALANCE MICROBIOME

FACTORS THAT CAN IMPACT THE SKIN MICROBIOME

Antibiotics and antimicrobial agents

The use of antibiotics and antimicrobial products can disrupt the balance of the skin microbiome by killing not only harmful bacteria but also beneficial ones. Prolonged or unnecessary use of such products can lead to an overgrowth of certain pathogens and a reduction in microbial diversity.

Topical skincare products

Harsh or inappropriate skincare products, particularly those with strong detergents and preservatives, can disturb the skin's pH balance and strip away natural oils that support the growth of beneficial microorganisms.

ATOPIC DERMATITIS AND SKIN MICROBIOME

Atopic dermatitis (AD) is one of the most common, chronic, inflammatory skin diseases of the modern world. Additionally known as ‘eczema’, this chronic recurrent disorder is characterized by an intense itching sensation and eczematous lesions. 

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Pathophysiology of AD is very complex and not yet completely elucidated. Multiple contributing factors, including epidermal barrier impairment, immune dysregulation and alteration of skin microbiota, contribute to the disease. 

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Over the last few years there have been scientific breakthroughs with reference to treating AD using oral or topical probiotic cultures. A number of topical probiotic formulations have been proposed to ameliorate skin conditions by suppressing inflammation and restoring skin microbiota balance.

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Even though the probiotic lysate used in topical cream is not technically probiotics, the probiotic bacteria preparations evidently have the ability to interact with the skin components and alleviate AD symptoms.

Reference: Skin Microbiota in Atopic Dermatitis

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THE SKIN MICROBIOME AND CANCER TREATMENT-RELATED SKIN TOXICITIES

The current literature found changes in the diversity and abundance of the skin microbiome during cancer treatments such as radiation therapy, including lower diversity of the skin microbiome, an increased Proteobacteria/Firmicutes ratio, and a higher abundance of pathogenic Staphylococcus aureus. These changes may be associated with the development and severity of treatment-related skin toxicities, such as acute radiation dermatitis, hand-foot syndrome in chemotherapy, and immunotherapy-induced rash.

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Most skin diseases or infections are associated with skin microbiome dysbiosis, a term that describes a disruption or imbalance in microbiota homeostasis. Proactive skincare is recommended by physicians for patients undergoing RT as these products aid in minimizing skin reactions by maintaining the epidermal barrier and possibly stabilizing microbial homeostasis.

Reference: Skin Microbiome and Treatment-Related Skin Toxicities in Patients With Cancer: A Mini-Review

SKIN’S MICROBIOME COULD HELP COMBAT SKIN AGING

A recent study published in the journal PLOS  has identified bacterial pathways associated with skin aging. The skin microbiome interacts with the body’s immune system and may affect its functioning. And the immune system regulates the makeup of the skin microbiome. The research data demonstrated that the main bacterial pathways related to aging involve the production of skin pigment, fatty acids, and ceramides. 

 

Increased wrinkles, decreased elasticity, reduced wound healing, and impaired barrier function are skin changes that occur during aging. Dry skin in elderly adults is very common; in fact, more than half of older adults have it. A loss of sweat and oil glands is one reason. Changes in the skin microbiome can also stem from a decline in the production of sebum, which is an oily substance that protects the skin, as well as from decreased water content in the skin and immune dysfunction.

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Reference: Medical New Today 

Harnessing the skin’s microbiome could help combat skin aging

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MAINTAIN A HEALTHY SKIN MICROBIOME

The skin microbiome is highly sensitive and can be influenced by various internal and external factors. Maintaining a healthy skin microbiome involves taking a holistic approach to skincare and overall health and adopting good skincare practices and making lifestyle choices that support a balanced and diverse microbial ecosystem on the skin. 

 

Using gentle and pH-balanced skincare products, avoiding unnecessary use of antibiotics or antimicrobial agents, eating a balanced diet, managing stress, and protecting the skin from environmental aggressors. If you have specific skin concerns, it's essential to consult with a dermatologist who can provide personalized advice and treatment options.

MOISTURISING REGULARLY

Keeping your skin well-hydrated helps maintain the skin's natural barrier and supports a healthy microbiome. Choose moisturisers with ingredients that nourish the skin without causing irritation.

GENTLE CLEANSING

Use mild, acidic pH (5-5.5) cleansers that are suitable for your skin type. Avoid harsh soaps and detergents that can disrupt the skin's natural barrier and strip away beneficial microorganisms.

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